SETD2 antibody

Catalog No. ABIN7075582

Product Details anti-SETD2 Antibody

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse KMT3A / HYPB / HIF-1

Application Details

Application Notes: WB (M) 1:300-1:500, IHC/IF (M) 1:1800-1:3600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Alternative Name: KMT3A / HYPB / HIF-1 (SETD2 Products)

Synonyms: Kif9 antibody, HBP231 antibody, HIF-1 antibody, HIP-1 antibody, HYPB antibody, KMT3A antibody, SET2 antibody, p231HBP antibody, SET domain containing 2 antibody, Setd2 antibody, SETD2 antibody

Background: SETD2, also named as HIF1, HYPB, KIAA1732, KMT3A, SET2, p231HBP, hSET2 and HIP-1, belongs to the histone-lysine methyltransferase family and SET2 subfamily. SETD2 probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. It binds DNA at promoters. SETD2 may also act as a transcription activator that binds to promoters. It is a potential tumour suppressor gene in breast cancer. This antibody is specific to SETD2.

Molecular Weight: 286 kDa

Gene ID: 235626

UniProt: E9Q5F9

Pathways: Tube Formation