SPATA13 antibody

Catalog No. ABIN7075700

Product Details anti-SPATA13 Antibody

Target: SPATA13 (Spermatogenesis Associated 13 (SPATA13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA13 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Asef2

Application Details

Application Notes: WB (H) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SPATA13

Target: SPATA13 (Spermatogenesis Associated 13 (SPATA13))

Alternative Name: Asef2 (SPATA13 Products)

Synonyms: ARHGEF29 antibody, ASEF2 antibody, C79050 antibody, ESTM11 antibody, X83327 antibody, mFLJ00298 antibody, spermatogenesis associated 13 antibody, SPATA13 antibody, Spata13 antibody

Background: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Molecular Weight: 75 kDa

Gene ID: 219140

NCBI Accession: NP_001028444

UniProt: Q5DU57