SYNPO2L antibody

Catalog No. ABIN7075791

Product Details anti-SYNPO2L Antibody

Target: SYNPO2L (Synaptopodin 2-Like (SYNPO2L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNPO2L antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse SYNPO2L

Application Details

Application Notes: WB (H,M,R) 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SYNPO2L

Target: SYNPO2L (Synaptopodin 2-Like (SYNPO2L))

Alternative Name: SYNPO2L (SYNPO2L Products)

Synonyms: 1110054M18Rik antibody, Chap antibody, synaptopodin 2 like antibody, synaptopodin 2-like antibody, SYNPO2L antibody, Synpo2l antibody

Background: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.

Molecular Weight: 70 kDa

Gene ID: 68760

NCBI Accession: NP_001297361

UniProt: Q8BWB1