MAPT antibody (pSer202, pThr205)

Catalog No. ABIN7075838

This Rabbit Polyclonal antibody specifically detects MAPT in WB, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for MAPT antibody (pSer202, pThr205) (ABIN7075838)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MAPT Antibody

Binding Specificity: pSer202, pThr205

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic phosphopeptide corresponding to Human TAU (S202/T205)

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:600-1:1200

Restrictions: For Research Use only

Handling

Buffer: , 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: TAU

Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity .The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both .Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Molecular Weight: 50-80 kDa

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size