TBC1D17 antibody

Catalog No. ABIN7075844

Product Details anti-TBC1D17 Antibody

Target: TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBC1D17 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TBC1D17

Application Details

Application Notes: WB (H,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TBC1D17

Target: TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))

Alternative Name: TBC1D17 (TBC1D17 Products)

Synonyms: BC017607 antibody, TBC1 domain family member 17 antibody, TBC1 domain family, member 17 antibody, TBC1D17 antibody, Tbc1d17 antibody

Background: Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.

Molecular Weight: 73 kDa

Gene ID: 233204

NCBI Accession: NP_001036120

UniProt: Q8BYH7