Tenascin R antibody

Catalog No. ABIN7075858

Product Details anti-Tenascin R Antibody

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tenascin R antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TNR

Application Details

Application Notes: WB (H,M,R) 1:300-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Tenascin R

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Alternative Name: TNR (TNR Products)

Synonyms: TN-R antibody, J1-tenascin antibody, janusin antibody, restrictin antibody, J1NRM antibody, tenascin R antibody, TNR antibody, Tnr antibody

Background: TNR, also named as Restrictin and Janusin, belongs to the tenascin family. Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides, TNR inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2 (FAK) phosphorylation and cell detachment.

Molecular Weight: 170 kDa

Gene ID: 21960

NCBI Accession: NP_071707

UniProt: Q8BYI9

Pathways: Regulation of Cell Size