TTC7A antibody
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- Target See all TTC7A Antibodies
- TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TTC7A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse TTC7A
- Top Product
- Discover our top product TTC7A Primary Antibody
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- Application Notes
- WB (H) 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))
- Alternative Name
- TTC7A (TTC7A Products)
- Synonyms
- 1110035E02Rik antibody, 1700007L07Rik antibody, Ttc7a antibody, fsn antibody, hea antibody, MINAT antibody, TTC7 antibody, Ttc7 antibody, tetratricopeptide repeat domain 7 antibody, tetratricopeptide repeat domain 7A antibody, Ttc7 antibody, TTC7A antibody, Ttc7a antibody
- Background
- TTC7A (TPR repeat protein 7A) is expressed in enterocytes within the duodenum, ileum, and colon, and has a role in enterocyte survival and function. Mutations in the TTC7A gene can result in a spectrum of intestinal disease, including multiple intestinal atresia (MIA) and very early onset inflammatory bowel diseases (VEOIBD). Functional analysis revealed that TTC7A binds to and facilitates the transport of PI4KIIIa from the trans-Golgi to the plasma membrane, while loss of TTC7A results in dysregulation of PI4KIIIa signaling. This antibody specially recognizes endogenous TTC7A.
- Molecular Weight
- 100 kDa
- Gene ID
- 225049
- NCBI Accession
- NP_082915
- UniProt
- Q8BGB2
- Pathways
- Transition Metal Ion Homeostasis
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