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CD73 antibody (APC-Cy7)
GMP Grade
NT5E
Reactivity: Human
FACS
Host: Mouse
Monoclonal
AD2
APC-Cy7
Product Details anti-CD73 Antibody (APC-Cy7)
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Target
See all CD73 (NT5E) Antibodies
CD73 (NT5E)
(5'-Nucleotidase, Ecto (CD73) (NT5E))
Reactivity
All reactivities for CD73 antibodies
Human
Host
All hosts for CD73 antibodies
Mouse
Clonality
All clonalities for CD73 antibodies
Monoclonal
Conjugate
All conjugates for CD73 antibodies
This CD73 antibody is conjugated to APC-Cy7
Application
All applications for CD73 antibodies
Flow Cytometry (FACS)
Purpose
CD73 APC-Cyanine 7 Antibody
Characteristics
The clone AD2, a mouse monoclonal antibody recognizes a 70kD glycophosphatidylinositol (GPI)-linked 5'nucleotidase (or 5'-Ecto-nucleotidase) cell surface antigen known as CD73. It is widely expressed on various immune as well as non-immune cells including T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, epithelial cells, etc. CD73 catalyzes the conversion of extracellular nucleosides to adenosine and modulates immune responses. Administration of CD73 inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells.
Purification
Purified
Purity
>95 %
Grade
GMP Grade
Immunogen
Pre-B leukemia cell line
Clone
AD2
Isotype
IgG1, kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
2-8°C, Conjugated antibodies should never be frozen.
Target Details for CD73
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Target
CD73 (NT5E)
(5'-Nucleotidase, Ecto (CD73) (NT5E))
Alternative Name
CD73 (NT5E Products )
Synonyms
CALJA antibody, CD73 antibody, E5NT antibody, NT antibody, NT5 antibody, NTE antibody, eN antibody, eNT antibody, zgc:63784 antibody, NT5E antibody, MGC114869 antibody, PSPTO2277 antibody, 2210401F01Rik antibody, AI447961 antibody, Nt5 antibody, 5'-nucleotidase ecto antibody, 5'-nucleotidase, ecto (CD73) antibody, 5'-nucleotidase antibody, 5' nucleotidase, ecto antibody, NT5E antibody, nt5e antibody, nt5e.S antibody, PSPTO_2277 antibody, CBU_1233 antibody, MCA1322 antibody, Nt5e antibody
Gene ID
4907
UniProt
P21589
Pathways
Synaptic Membrane , Ribonucleoside Biosynthetic Process
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