GZMB antibody (AA 21-130) (PE)
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- Target See all GZMB Antibodies
- GZMB (Granzyme B (GZMB))
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Binding Specificity
- AA 21-130
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GZMB antibody is conjugated to PE
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Specificity
- Specific towards Granzyme B and Granzyme H
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GZMB
- Isotype
- IgG
- Top Product
- Discover our top product GZMB Primary Antibody
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- Application Notes
- FCM 1:20-100
- Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- Granzyme B (GZMB Products)
- Synonyms
- CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
- Background
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Synonyms: HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, T-cell serine protease 1-3E, GZMB, GRB, Granzyme B, Granzyme H
Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
- Gene ID
- 3002
- UniProt
- P10144
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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