MGMT antibody (AA 1-100)
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- Target See all MGMT Antibodies
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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Binding Specificity
- AA 1-100
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MGMT antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from mouse MGMT
- Isotype
- IgG
- Top Product
- Discover our top product MGMT Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000 - Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Alternative Name
- MGMT (MGMT Products)
- Synonyms
- AGT antibody, AI267024 antibody, Agat antibody, O-6-methylguanine-DNA methyltransferase antibody, MGMT antibody, Mgmt antibody
- Background
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Synonyms: 6 O methylguanine DNA methyltransferase, Agat, AGT, AI267024, EC 2.1.1.63, Methylated DNA protein cysteine methyltransferase, Methylguanine DNA methyltransferase, MGC107020, MGMT: O-6 methylguanine DNA methyltransferase, O 6 methylguanine DNA alkyltransferase, O 6 methylguanine DNA methyltransferase, O-6 methylguanine DNA alkyltransferase, O-6-methylguanine-DNA methyltransferase, O6 methylguanine DNA methyltransferase, MGMT_HUMAN.
Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
- Gene ID
- 17314
- UniProt
- P26187
- Pathways
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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