TBP antibody (Biotin)
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- Target See all TBP Antibodies
- TBP (TATA Box Binding Protein (TBP))
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TBP antibody is conjugated to Biotin
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein G.
- Immunogen
- Recombinant human TBP protein
- Clone
- 6G8
- Isotype
- IgG
- Top Product
- Discover our top product TBP Primary Antibody
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- TBP (TATA Box Binding Protein (TBP))
- Alternative Name
- TATA binding protein TBP/TBP (TBP Products)
- Synonyms
- GTF2D antibody, GTF2D1 antibody, HDL4 antibody, SCA17 antibody, TFIID antibody, Gtf2d antibody, fd20h06 antibody, si:zc101n13.2 antibody, wu:fd20h06 antibody, zgc:66213 antibody, TBP1 antibody, TBP antibody, tbp antibody, CG9874 antibody, Dmel\\CG9874 antibody, RBP antibody, TBP38 antibody, TFIIDtau antibody, TfIID antibody, dTBP antibody, dTFIID antibody, dTbp antibody, dtbp antibody, gtf2d antibody, gtf2d1 antibody, sca17 antibody, tfiid antibody, tfiidtau antibody, xtbp antibody, tbp-a antibody, tbp-b antibody, TATA-box binding protein antibody, TATA box binding protein antibody, TATA binding protein antibody, TATA-box binding protein L homeolog antibody, TATA-box-binding protein antibody, TATA-box binding protein S homeolog antibody, TBP antibody, Tbp antibody, tbp antibody, tbp.L antibody, tbp.S antibody
- Background
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Synonyms: GTF2D, TFIID, GTF2D1, MGC117320, MGC126054, MGC126055, SCA 17, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA binding protein TBP, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TBP_HUMAN, TF2D, TFIID, Transcription initiation factor TFIID TBP subunit.
Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]
- Gene ID
- 6908
- UniProt
- P20226
- Pathways
- WNT Signaling
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