gamma Tubulin antibody (Cy3)
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- Target See all gamma Tubulin (TUBG) products
- gamma Tubulin (TUBG) (Tubulin, gamma (TUBG))
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Reactivity
- Mouse, Human, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This gamma Tubulin antibody is conjugated to Cy3
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Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein G.
- Immunogen
- KLH conjugated synthetic peptide derived from human Gamma Tubulin
- Clone
- 8D11
- Isotype
- IgG
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- Target
- gamma Tubulin (TUBG) (Tubulin, gamma (TUBG))
- Alternative Name
- Gamma Tubulin (TUBG Products)
- Synonyms
- Tubg2 antibody, xgam antibody, tubulin gamma 1 L homeolog antibody, tubg1.L antibody
- Background
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Synonyms: Centrosome Marker, Gamma 1 tubulin, gamma tubulin, gamma-tubulin, Gamma 2 tubulin, Gamma Tubulin 1, Gamma Tubulin 2, Gamma tubulin complex component 1, GCP 1, GCP-1, GCP1, MGC131994, TUBG, TUBG1, TUBG2, Tubulin gamma 1 chain, Tubulin gamma 2 chain, Xgam, TBG1_HUMAN, TBG2_HUMAN, Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1.
Background: Centrosome Marker
Gamma tubulin, a member of the tubulin superfamily, is a ubiquitous and highly conserved protein within the microtubule organizing centre (MTOC). Gamma tubulin is not a component of microtubules, rather it functions as the microtubule nucleator at the MOTC, is responsible for binding microtubule minus ends and mediating the link between microtubles and the centrosome. By binding to the beta tubulin subunit of the tubulin molecule, it establishes the polarity of a microtubule leaving the alpha tubulin subunit exposed at the positive end.
The abundance of Gamma tubulin is less than 1 % of the level of either alpha or beta tubulin. It shares approximately 28-32 % identity with alpha tubulin from various organisms and 32-36 % identity with beta tubulins. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis and the microtubule cytoskeleton. - Gene ID
- 7283
- UniProt
- P23258
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