Huntingtin antibody (AA 2845-3000)

Catalog No. ABIN7115121

The Rabbit Polyclonal anti-Huntingtin antibody (ABIN7115121) specifically detects Huntingtin in IHC, WB, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for Huntingtin antibody (AA 2845-3000) (ABIN7115121)

Target: Huntingtin (HTT)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Huntingtin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Huntingtin Antibody

Binding Specificity: AA 2845-3000

Purpose: HTT antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 2845-3000aa

Immunogen: Huntingtin

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50-1:500, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Huntingtin

Target: Huntingtin (HTT)

Alternative Name: HTT

Background:

Synonyms: Huntingtin|Huntington disease protein (HD protein)|Huntingtin, myristoylated N-terminal fragment|HTT|HD|IT15

Background: HTT(huntingtin), also named as HD and IT15, belongs to the huntingtin family. HTT may play a role in microtubule-mediated transport or vesicle function. Defects in HTT are the cause of Huntington disease (HD) which is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia.

Molecular Weight: 348 kDa

Gene ID: 3064

UniProt: P42858

Pathways: PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport