ITM2C antibody

Catalog No. ABIN7115302

Product Details anti-ITM2C Antibody

Target: ITM2C (Integral Membrane Protein 2C (ITM2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITM2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: integral membrane protein 2C

Clone: 5D9

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ITM2C

Target: ITM2C (Integral Membrane Protein 2C (ITM2C))

Alternative Name: ITM2C (ITM2C Products)

Synonyms: 3110038L02Rik antibody, BRI3 antibody, Bricd2c antibody, E25 antibody, E25C antibody, ITM3 antibody, BRICD2C antibody, fj35c02 antibody, itm2c antibody, wu:fj35c02 antibody, zgc:66349 antibody, wu:fj52a04 antibody, zgc:92783 antibody, integral membrane protein 2C antibody, integral membrane protein 2Cb antibody, integral membrane protein 2Ca antibody, Itm2c antibody, ITM2C antibody, itm2cb antibody, itm2ca antibody

Background: Synonyms:BRI3 Background:Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation(By similarity).

Molecular Weight: 35 kDa

Gene ID: 81618

UniProt: Q9NQX7