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KIAA0586 antibody

KIAA0586 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7115666
  • Target See all KIAA0586 products
    KIAA0586
    Reactivity
    Human, Mouse
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    ELISA, Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    KIAA0586
    Isotype
    IgG
  • Application Notes
    IHC: 1:50-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    KIAA0586
    Alternative Name
    TALPID3 (KIAA0586 Products)
    Synonyms
    Talpid3 antibody, KIAA0586 antibody, KIAA0586 antibody
    Background
    Synonyms: Background:Required for ciliogenesis and sonic hedgehog/SHH signaling(PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation(By similarity). Involved in regulation of cell intracellular organization(PubMed:26386247). Involved in regulation of cell polarity(By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles(PubMed:25251415).
    Gene ID
    76967
    UniProt
    E9PV87
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