NCOA6 antibody

Catalog No. ABIN7116987

Product Details anti-NCOA6 Antibody

Target: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA6 antibody is un-conjugated

Application: ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: nuclear receptor coactivator 6

Isotype: IgG

Application Details

Application Notes: IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for NCOA6

Target: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Alternative Name: NCOA6 (NCOA6 Products)

Synonyms: gb:dq017635 antibody, wu:fb25d11 antibody, ncoa6 antibody, AIB3 antibody, ASC2 antibody, NRC antibody, PRIP antibody, RAP250 antibody, TRBP antibody, ASC-2 antibody, Ncoa7 antibody, mKIAA0181 antibody, Aib3 antibody, Trbp antibody, nuclear receptor coactivator 6 antibody, NCOA6 antibody, Tsp_14219 antibody, Tsp_13372 antibody, ncoa6 antibody, LOC100196047 antibody, Ncoa6 antibody

Background: Synonyms:AIB3, KIAA0181, RAP250, TRBP Background:Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist-and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ERs), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Molecular Weight: 68 kDa , 219 kDa , 110 kDa

Gene ID: 23054

UniProt: Q14686

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha