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NUDT3 antibody
NUDT3
Reactivity: Human, Mouse
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NUDT3 Antibody
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Target
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NUDT3
(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 (NUDT3))
Reactivity
All reactivities for NUDT3 antibodies
Human, Mouse
Host
All hosts for NUDT3 antibodies
Rabbit
Clonality
All clonalities for NUDT3 antibodies
Polyclonal
Conjugate
All conjugates for NUDT3 antibodies
This NUDT3 antibody is un-conjugated
Application
All applications for NUDT3 antibodies
Western Blotting (WB), ELISA
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
nudix(nucleoside diphosphate linked moiety X)-type motif 3
Isotype
IgG
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Application Details
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Application Notes
WB: 1:500-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for NUDT3
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Target
NUDT3
(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 (NUDT3))
Alternative Name
NUDT3 (NUDT3 Products )
Synonyms
DIPP antibody, DIPP-1 antibody, DIPP1 antibody, 1110011B09Rik antibody, AA960325 antibody, Dipp antibody, NUDT3 antibody, zgc:55746 antibody, zgc:103443 antibody, nudix hydrolase 3 antibody, nudix (nucleotide diphosphate linked moiety X)-type motif 3 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 3a antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 3b antibody, NUDT3 antibody, Nudt3 antibody, nudt3a antibody, nudt3b antibody
Background
Synonyms:DIPP, DIPP1 Background:Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5(diphosphoinositol pentakisphosphate) and [PP]2-InsP4(bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6(inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Molecular Weight
20-30kd
Gene ID
11165
UniProt
O95989
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