NUDT3 antibody

Catalog No. ABIN7468692

Product Details anti-NUDT3 Antibody

Target: NUDT3 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 (NUDT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUDT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NUDT3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IMR32

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NUDT3

Target: NUDT3 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 (NUDT3))

Alternative Name: nudix hydrolase 3 (NUDT3 Products)

Synonyms: DIPP antibody, DIPP-1 antibody, DIPP1 antibody, 1110011B09Rik antibody, AA960325 antibody, Dipp antibody, NUDT3 antibody, zgc:55746 antibody, zgc:103443 antibody, nudix hydrolase 3 antibody, nudix (nucleotide diphosphate linked moiety X)-type motif 3 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 3a antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 3b antibody, NUDT3 antibody, Nudt3 antibody, nudt3a antibody, nudt3b antibody

Background:

Synonyms: nudix hydrolase 3 , DIPP , DIPP-1 , DIPP1

Background: NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]).[supplied by OMIM]

Molecular Weight: 19 kDa

Gene ID: 11165

UniProt: O95989