PTGES3 antibody

Catalog No. ABIN7117865

Product Details anti-PTGES3 Antibody

Target: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGES3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: prostaglandin E synthase 3(cytosolic)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PTGES3

Target: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Alternative Name: PTGES3 (PTGES3 Products)

Synonyms: P23 antibody, TEBP antibody, cPGES antibody, PTGES3 antibody, 5730442A20Rik antibody, Ptges antibody, Tebp antibody, p23 antibody, sid3177 antibody, RGD1561913 antibody, CPGES antibody, cPGES-1 antibody, ptges3 antibody, wu:fb98d06 antibody, zgc:65804 antibody, zgc:77131 antibody, tebp antibody, wu:fb50a04 antibody, zgc:86751 antibody, prostaglandin E synthase 3 antibody, prostaglandin E synthase 3 (cytosolic) pseudogene antibody, prostaglandin E synthase 3a (cytosolic) antibody, prostaglandin E synthase 3 L homeolog antibody, prostaglandin E synthase 3b (cytosolic) antibody, PTGES3 antibody, LOC743066 antibody, Ptges3 antibody, ptges3a antibody, ptges3.L antibody, ptges3b antibody

Background: Synonyms:P23, TEBP Background:Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2(PGH2) to prostaglandin E2(PGE2)(PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes(PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway(PubMed:24711448).

Molecular Weight: 21-23 kDa

Gene ID: 10728

UniProt: Q15185

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cellular Glucan Metabolic Process