SERPINC1 antibody

Catalog No. ABIN7118893

Product Details anti-SERPINC1 Antibody

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SERPINC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: serpin peptidase inhibitor, clade C(antithrombin), member 1

Clone: 9A4

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Alternative Name: Antithrombin III (SERPINC1 Products)

Synonyms: AT3 antibody, AT3D antibody, ATIII antibody, THPH7 antibody, SERPINC1 antibody, DKFZp470C1733 antibody, AI114908 antibody, At-3 antibody, At3 antibody, ANTITHROMBIN, AT-III antibody, AT-III antibody, serpin family C member 1 antibody, antithrombin-III antibody, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antibody, SERPINC1 antibody, CpipJ_CPIJ000472 antibody, CpipJ_CPIJ013111 antibody, Serpinc1 antibody

Background: Synonyms:Antithrombin, Antithrombin III, AT3, ATIII, HEPARIN COFACTOR I, Serpin C1, SERPINC1 Background:SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Molecular Weight: 53 kDa

Gene ID: 462

UniProt: P01008