SH3BP4 antibody

Catalog No. ABIN7119024

Product Details anti-SH3BP4 Antibody

Target: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SH3-domain binding protein 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SH3BP4

Target: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Alternative Name: SH3BP4 (SH3BP4 Products)

Synonyms: BOG25 antibody, TTP antibody, AI594717 antibody, AW227605 antibody, SH3BP4 antibody, bog25 antibody, ttp antibody, LOC569399 antibody, sh3bp4 antibody, SH3 domain binding protein 4 antibody, SH3-domain binding protein 4 antibody, SH3-domain binding protein 4 L homeolog antibody, SH3BP4 antibody, Sh3bp4 antibody, sh3bp4 antibody, sh3bp4.L antibody

Background: Synonyms:BOG25, EHB10, TTP Background:May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.

Molecular Weight: 120 kDa

Gene ID: 23677

UniProt: Q9P0V3