DP2 antibody

Catalog No. ABIN7120073

Product Details anti-DP2 Antibody

Target: DP2 (TFDP2) (Transcription Factor Dp-2 (E2F Dimerization Partner 2) (TFDP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: transcription factor Dp-2(E2F dimerization partner 2)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for DP2

Target: DP2 (TFDP2) (Transcription Factor Dp-2 (E2F Dimerization Partner 2) (TFDP2))

Alternative Name: TFDP2 (TFDP2 Products)

Synonyms: dp2 antibody, dp-2 antibody, 1110029I05Rik antibody, A330080J22Rik antibody, DP-3 antibody, DP3 antibody, DP2 antibody, Tcfdp2 antibody, transcription factor Dp-2 antibody, transcription factor Dp-2 S homeolog antibody, transcription factor Dp 2 antibody, TFDP2 antibody, tfdp2 antibody, tfdp2.S antibody, Tfdp2 antibody

Background: Synonyms:DP2 Background:Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters(PubMed:20176812).

Molecular Weight: 49 kDa

Gene ID: 7029

UniProt: Q14188

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases