FERMT2 antibody (AA 218-486)

Catalog No. ABIN7126209

Product Details anti-FERMT2 Antibody

Target: FERMT2 (Fermitin Family Member 2 (FERMT2))

Binding Specificity: AA 218-486

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FERMT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: Kindlin-2 (also known as Mig-2, KIND2) is an important component of cell-extracellular matrix adhesion. Kindlin-2 binds integrins and is involved in ECM adhesion, actin assembly and cell shape modulation. This monoclonal antibody recognizes kindlin-2 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.

Cross-Reactivity (Details): Human. Mouse. Rat. Bovine. Hamster.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant protein containing MIG-2 (residues 218-486)

Isotype: IgG1

Application Details

Application Notes:

Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: 293T whole cell lysate. Human tonsil or liver.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for FERMT2

Target: FERMT2 (Fermitin Family Member 2 (FERMT2))

Alternative Name: FERMT2 (FERMT2 Products)

Synonyms: AA960555 antibody, Kindlin-2 antibody, Mig2 antibody, Plekhc1 antibody, KIND2 antibody, MIG2 antibody, PLEKHC1 antibody, UNC112 antibody, UNC112B antibody, mig-2 antibody, fermitin family member 2 antibody, Fermt2 antibody, FERMT2 antibody

Background: Fermitin family homolog 2 (Fermt2), Kindlin-2 (KIND2), Mitogen-inducible gene 2 protein (MIG2), Pleckstrin homology domain containing family C (with FERM domain) member 1 (PLEKHC1),Kindlin-2 / KIND2
Cellular localisation: Cytoplasm.

Molecular Weight: 78kDa

Gene ID: 10979, 509343

UniProt: Q96AC1

Pathways: Cell-Cell Junction Organization