Retinoid X Receptor beta antibody
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- Target See all Retinoid X Receptor beta (RXRB) Antibodies
- Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Retinoid X Receptor beta antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)
- Specificity
- Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARi±, RARi² and RARi³, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human RXRB protein
- Isotype
- IgG2a
- Top Product
- Discover our top product RXRB Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))
- Alternative Name
- RXRB (RXRB Products)
- Synonyms
- DAUDI6 antibody, H-2RIIBP antibody, NR2B2 antibody, RCoR-1 antibody, RXR-beta antibody, RXRbeta antibody, rxrb antibody, RXRB antibody, nr2b2 antibody, daudi6 antibody, rcor-1 antibody, h-2riibp antibody, NR2B2-A antibody, RXR antibody, RXRA antibody, etID309733.19 antibody, rxre antibody, wu:fb93c09 antibody, AL023085 antibody, Nr2b2 antibody, Rub antibody, rxrd antibody, unp286 antibody, retinoid X receptor beta antibody, retinoid X receptor beta S homeolog antibody, retinoid x receptor, beta a antibody, retinoid x receptor, beta b antibody, RXRB antibody, Rxrb antibody, rxrb.S antibody, rxrb antibody, rxrba antibody, rxrbb antibody
- Background
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DAUDI6, H2RIIBP, MGC1831, MHC class I promoter binding protein, NR2B2, nuclear receptor subfamily 2 group B member 2, RCoR1, Retinoic acid receptor RXR beta, RXR beta,RXRB
Cellular localisation: Nucleus. - Molecular Weight
- 50-54kDa
- Gene ID
- 6257, 388034
- UniProt
- P28702
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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