Retinoid X Receptor gamma antibody
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- Target See all Retinoid X Receptor gamma (RXRG) Antibodies
- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Retinoid X Receptor gamma antibody is un-conjugated
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Application
- ELISA, Immunoprecipitation (IP), Coating (Coat), Flow Cytometry (FACS)
- Specificity
- Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
- Cross-Reactivity (Details)
- Human. Predicted to react in Mouse, Rat and Chick.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human RXRG protein
- Isotype
- IgG2b
- Top Product
- Discover our top product RXRG Primary Antibody
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- Application Notes
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), ,Optimal dilution for a specific application should be determined.
Positive_Control: SK-MEL-30, U-2 OS or HeLa cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
- Alternative Name
- RXRG (RXRG Products)
- Synonyms
- NR2B3 antibody, RXRC antibody, zgc:92183 antibody, RXRgamma antibody, RXRG antibody, RXR-gamma antibody, nr2b3 antibody, xrxrg antibody, rxrc antibody, Nr2b3 antibody, NR2B1 antibody, RXR antibody, rxra antibody, rxrg antibody, retinoid X receptor gamma antibody, retinoid X receptor, gamma b antibody, retinoid X receptor gamma L homeolog antibody, retinoid x receptor, gamma a antibody, RXRG antibody, rxrgb antibody, rxrg.L antibody, rxrg antibody, Rxrg antibody, RXRGAMMA antibody, rxrga antibody
- Background
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Nuclear receptor subfamily 2 group B member 3 (NR2B3), Retinoic X receptor gamma (RXRG), Retinoic acid receptor RXR gamma, RXR gamma, RXRC,RXRG / NR2B3 (Transcription Factor)
Cellular localisation: Nucleus > Nucleoplasm > Nuclear bodies. - Molecular Weight
- 50.87kDa
- Gene ID
- 6258, 26550
- UniProt
- P48443
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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