Recombinant BPIFB1 antibody

Catalog No. ABIN7127158

Product Details anti-BPIFB1 Antibody

Target: BPIFB1 (BPI Fold Containing Family B, Member 1 (BPIFB1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BPIFB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: The upper respiratory tract is the main place of entry for pathogens to invade the body, and early recognition of bacterial products in this region is crucial for host defense. Palate lung nasal epithelial clone PLUNC (or LUNX) is an airway specific secretory protein that is expressed in epithelial tissues and submucosal glands of the oral cavity and upper respiratory tract of humans, mice, rats and cows. PLUNC binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of PLUNC occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of PLUNC in the upper respiratory tract. Abnormal expression of PLUNC may influence susceptibility to nasopharyngeal carcinoma in the Chinese population.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human BPIFB1 protein

Isotype: IgG

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human lung or tonsil. HeLa cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for BPIFB1

Target: BPIFB1 (BPI Fold Containing Family B, Member 1 (BPIFB1))

Alternative Name: BPIFB1 (BPIFB1 Products)

Synonyms: C20orf114 antibody, LPLUNC1 antibody, Lplunc1 antibody, C13H20orf114 antibody, RGD1563047 antibody, BPI fold containing family B member 1 antibody, BPI fold containing family B, member 1 antibody, BPIFB1 antibody, Bpifb1 antibody

Background: BPI fold containing family B, member 1, Long palate, lung and nasal epithelium carcinoma associated protein 1 (Lplunc1), lung and nasal epithelium carcinoma-associated protein 1, VEMSGP, Von Ebner minor salivary gland protein,L-PLUNC
Cellular localisation: Secreted.

Molecular Weight: 25kDa

Gene ID: 92747, 65551

UniProt: Q8TDL5