Recombinant AGT antibody

Catalog No. ABIN7127340

The Rabbit Monoclonal anti-AGT antibody is suitable to detect AGT in samples from Human. It has been validated for IHC and ELISA.

Quick Overview for Recombinant AGT antibody (ABIN7127340)

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This AGT antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 8A9

Product Details anti-AGT Antibody

Purpose: AGT Recombinant Monoclonal Antibody

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Angiotensinogen

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AGT

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Alternative Name: AGT

Background:

Background: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.

Aliases: Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I), Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II), Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II), Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV), Angiotensin 1-9, Angiotensin 1-7, Angiotensin 1-5, Angiotensin 1-4], AGT, SERPINA8

UniProt: P01019

Pathways: JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity