KIR2DL3 antibody (Internal Region)

Catalog No. ABIN7128095

Product Details anti-KIR2DL3 Antibody

Target: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIR2DL3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen Affinity Purified

Immunogen: Fusion protein corresponding to a region derived from internal residues of Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3/1/4/ short cytoplasmic tail, 4

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in pH 7.3 PBS, 0.05 % Sodium azide, 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KIR2DL3

Target: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Alternative Name: KIR2DL3 (KIR2DL3 Products)

Synonyms: CD158B2 antibody, CD158b antibody, GL183 antibody, KIR-023GB antibody, KIR-K7b antibody, KIR-K7c antibody, KIRCL23 antibody, NKAT antibody, NKAT2 antibody, NKAT2A antibody, NKAT2B antibody, p58 antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 antibody, KIR2DL3 antibody

Background:

Background: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain."

Aliases: CD158 antigen like family member B2 antibody, CD158 antigen-like family member B2 antibody, CD158b antibody, CD158b2 antibody, GL183 antibody, KI2L3_HUMAN antibody, Killer cell immunoglobulin like receptor two domains long cytoplasmic tail 3 antibody, Killer cell immunoglobulin-like receptor 2DL3 antibody, Killer inhibitory receptor cl 2-3 antibody, Killer inhibitory receptor CL2 3 antibody, KIR 023GB antibody, KIR-023GB antibody, KIR-K7b antibody, KIR-K7c antibody, KIR023GB antibody, KIR2DL3 antibody, KIR2DS5 antibody, KIRCL23 antibody, MHC class I NK cell receptor antibody, Natural killer associated transcript 2 antibody, Natural killer cell inhibitory receptor KIR2DL3 antibody, Natural killer-associated transcript 2 antibody, NKAT antibody, NKAT-2 antibody, NKAT2 antibody, NKAT2a antibody, NKAT2b antibody, p58 antibody, p58 natural killer cell receptor clone CL 6 antibody, p58 natural killer cell receptor clone CL-6 antibody, p58 NK Receptor antibody, p58 NK receptor CL 6 antibody, p58 NK receptor CL-6 antibody, p58.2 MHC class I specific NK receptor antibody, p58.2 MHC class-I-specific NK receptor antibody

UniProt: P43628

Pathways: Cancer Immune Checkpoints