BMPR2 antibody

Catalog No. ABIN7128670

Product Details anti-BMPR2 Antibody

Target: BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMPR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human BMPR2

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BMPR2

Target: BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Alternative Name: BMPR2 (BMPR2 Products)

Synonyms: BMPR-II antibody, BMPR3 antibody, BMR2 antibody, BRK-3 antibody, PPH1 antibody, T-ALK antibody, 2610024H22Rik antibody, AL117858 antibody, AW546137 antibody, BB189135 antibody, BMP-2 antibody, BMPR-2 antibody, BMPRII antibody, Gm20272 antibody, Bmpr-II antibody, bmprii antibody, bone morphogenetic protein receptor type 2 antibody, bone morphogenetic protein receptor, type II b (serine/threonine kinase) antibody, bone morphogenetic protein receptor, type II (serine/threonine kinase) antibody, BMPR2 antibody, bmpr2b antibody, Bmpr2 antibody

Background:

Background: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Aliases: BMP type II receptor antibody, BMP type-2 receptor antibody, BMPR 2 antibody, BMPR 3 antibody, BMPR II antibody, BMPR-2 antibody, BMPR-II antibody, Bmpr2 antibody, BMPR2_HUMAN antibody, BMPR3 antibody, BMPRII antibody, BMR 2 antibody, BMR2 antibody, Bone morphogenetic protein receptor type 2 antibody, Bone morphogenetic protein receptor type II antibody, Bone morphogenetic protein receptor type-2 antibody, Bone morphogenic protein receptor type II serine threonine kinase antibody, BRK 3 antibody, BRK3 antibody, PPH 1 antibody, PPH1 antibody, Serine threonine kinase type II activin receptor like kinase antibody, T ALK antibody, TALK antibody, Type II activin receptor like kinase antibody

UniProt: Q13873

Pathways: Growth Factor Binding