CATSPER3 antibody

Catalog No. ABIN7128794

Product Details anti-CATSPER3 Antibody

Target: CATSPER3 (Cation Channel, Sperm Associated 3 (CATSPER3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CATSPER3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human CATSPER3

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, WB:1:500-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CATSPER3

Target: CATSPER3 (Cation Channel, Sperm Associated 3 (CATSPER3))

Alternative Name: CATSPER3 (CATSPER3 Products)

Synonyms: CATSPER3 antibody, CACRC antibody, 4921522D01Rik antibody, cation channel sperm associated 3 antibody, cation channel, sperm associated 3 antibody, CATSPER3 antibody, Catsper3 antibody

Background:

Background: CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.

Aliases: Ca(v)-like protein antibody, CACRC antibody, calcium channel repeat containing 1 antibody, Cation channel sperm-associated protein 3 antibody, Cation channel, sperm associated 3 antibody, CatSper3 antibody, CTSR3_HUMAN antibody, One-repeat calcium channel-like protein antibody, putative ion channel CatSper3 antibody

UniProt: Q86XQ3