PHLPP1 antibody

Catalog No. ABIN7130610

Product Details anti-PHLPP1 Antibody

Target: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHLPP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human PHLPP1

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PHLPP1

Target: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Alternative Name: PHLPP1 (PHLPP1 Products)

Synonyms: PHLPP antibody, PLEKHE1 antibody, SCOP antibody, AI836256 antibody, Phlpp antibody, Plekhe1 antibody, mKIAA0606 antibody, Scop antibody, PH domain and leucine rich repeat protein phosphatase 1 antibody, PHLPP1 antibody, phlpp1 antibody, Phlpp1 antibody

Background:

Background: This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Aliases: hSCOP antibody, KIAA0606 antibody, PH domain and leucine rich repeat protein phosphatase antibody, PH domain leucine rich repeat containing protein phosphatase antibody, PH domain leucine rich repeat protein phosphatase antibody, PH domain leucine-rich repeat-containing protein phosphatase 1 antibody, PH domain-containing family E member 1 antibody, PHLP1_HUMAN antibody, PHLPP antibody, Phlpp1 antibody, Pleckstrin homology domain containing family E (with leucine rich repeats) member 1 antibody, Pleckstrin homology domain containing family E protein 1 antibody, Pleckstrin homology domain-containing family E member 1 antibody, PLEKHE 1 protein antibody, PLEKHE1 antibody, SCN circadian oscillatory protein antibody, SCOP antibody, Suprachiasmatic nucleus circadian oscillatory protein antibody, Suprachiasmatic nucleus circadian protein antibody

UniProt: O60346

Pathways: PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway