RAMP3 antibody

Catalog No. ABIN7130809

Product Details anti-RAMP3 Antibody

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAMP3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human RAMP3

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RAMP3

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Alternative Name: RAMP3 (RAMP3 Products)

Synonyms: RAMP3 antibody, ramp3 antibody, AI850306 antibody, receptor activity modifying protein 3 antibody, receptor (G protein-coupled) activity modifying protein 3 antibody, Receptor activity-modifying protein 3 antibody, receptor (calcitonin) activity modifying protein 3 antibody, RAMP3 antibody, ramp3 antibody, Ramp3 antibody

Background:

Background: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

Aliases: RAMP3 antibody, Receptor activity-modifying protein 3 antibody, Calcitonin-receptor-like receptor activity-modifying protein 3 antibody, CRLR activity-modifying protein 3 antibody

UniProt: O60896

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling