RASGEF1A antibody

Catalog No. ABIN7130823

Product Details anti-RASGEF1A Antibody

Target: RASGEF1A (RasGEF Domain Family, Member 1A (RASGEF1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASGEF1A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human RASGEF1A

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:20-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RASGEF1A

Target: RASGEF1A (RasGEF Domain Family, Member 1A (RASGEF1A))

Alternative Name: RASGEF1A (RASGEF1A Products)

Synonyms: MGC84301 antibody, CG4853 antibody, 6330404M18Rik antibody, AI835194 antibody, RasGEF domain family member 1A antibody, RasGEF domain family member 1A L homeolog antibody, RasGEF domain family, member 1A antibody, RASGEF1A antibody, rasgef1a.L antibody, rasgef1a antibody, Rasgef1a antibody

Background:

Background: RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.

Aliases: CG4853 gene product antibody, Ras-GEF domain-containing family member 1A antibody, RasGEF domain family, member 1A antibody, rasgef1a antibody, RGF1A_HUMAN antibody

UniProt: Q8N9B8