SETD2 antibody

Catalog No. ABIN7131042

Product Details anti-SETD2 Antibody

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human SETD2

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Alternative Name: SETD2 (SETD2 Products)

Synonyms: Kif9 antibody, HBP231 antibody, HIF-1 antibody, HIP-1 antibody, HYPB antibody, KMT3A antibody, SET2 antibody, p231HBP antibody, SET domain containing 2 antibody, Setd2 antibody, SETD2 antibody

Background:

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Aliases: EC 2.1.1.43 antibody, FLJ16420 antibody, FLJ22472 antibody, FLJ23184 antibody, FLJ45883 antibody, HBP231 antibody, HIF 1 antibody, HIF-1 antibody, HIF1 antibody, HIP-1 antibody, Histone lysine N methyltransferase SETD2 antibody, Histone-lysine N-methyltransferase SETD2 antibody, hSET2 antibody, HSPC069 antibody, Huntingtin interacting protein 1 antibody, Huntingtin interacting protein antibody, Huntingtin interacting protein B antibody, Huntingtin interacting protein HYPB antibody, Huntingtin yeast partner B antibody, Huntingtin-binding protein, 231-KD antibody, Huntingtin-interacting protein 1 antibody, Huntingtin-interacting protein B antibody, HYPB antibody, KIAA1732 antibody, KMT3A antibody, Lysine N methyltransferase 3A antibody, Lysine N-methyltransferase 3A antibody, p231HBP antibody, SET domain containing 2 antibody, SET domain-containing protein 2 antibody, SET2 antibody, SETD2 antibody, SETD2_HUMAN antibody

UniProt: Q9BYW2

Pathways: Tube Formation