TBC1D22A antibody

Catalog No. ABIN7131302

Product Details anti-TBC1D22A Antibody

Target: TBC1D22A (TBC1 Domain Family, Member 22A (TBC1D22A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBC1D22A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human TBC1D22A

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TBC1D22A

Target: TBC1D22A (TBC1 Domain Family, Member 22A (TBC1D22A))

Alternative Name: TBC1D22A (TBC1D22A Products)

Synonyms: C22orf4 antibody, HSC79E021 antibody, BC023106 antibody, D15Ertd781e antibody, RGD1306588 antibody, TBC1 domain family member 22A antibody, TBC1 domain family, member 22a antibody, TBC1D22A antibody, Tbc1d22a antibody

Background:

Background: TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members. Multiple isoforms of TBC1D22A exist due to alternative splicing events. The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Aliases: TBC1D22A antibody, C22orf4 antibody, TBC1 domain family member 22A antibody

UniProt: Q8WUA7