c-MET antibody

Catalog No. ABIN7137922

This anti-c-MET antibody is a Rabbit Polyclonal antibody detecting c-MET in WB, ELISA and IHC. Suitable for Human.

Quick Overview for c-MET antibody (ABIN7137922)

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-MET antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-c-MET Antibody

Purpose: MET (Ab-1003) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa. 1001~1005 (V-D-Y-R-A) derived from Human Met.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Alternative Name: MET

Background:

Background: Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

Weidner, K.M. et al. (1993) J. Cell Biol. 121, 145-154.
Traxler, P. et al. (2001) Med. Res. Rev. 21, 499-512.
Schaeper, U. et al. (2000) J. Cell Biol. 149, 1419-1432.
Park, M. et al. (1986) Cell 45, 895-904.

Aliases: AUTS9 antibody, c met antibody, D249 antibody, Hepatocyte growth factor receptor antibody, HGF antibody, HGF receptor antibody, HGF/SF receptor antibody, HGFR antibody, MET antibody, Met proto oncogene antibody, Met proto oncogene tyrosine kinase antibody, MET proto oncogene, receptor tyrosine kinase antibody, Met proto-oncogene (hepatocyte growth factor receptor) antibody, Met proto-oncogene antibody, Met protooncogene antibody, MET_HUMAN antibody, Oncogene MET antibody, Par4 antibody, Proto-oncogene c-Met antibody, RCCP2 antibody, Scatter factor receptor antibody, SF receptor antibody, Tyrosine-protein kinase Met antibody

UniProt: P08581

Pathways: RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor