JAK1 antibody

Catalog No. ABIN7137924

The Rabbit Polyclonal anti-JAK1 antibody has been validated for WB, IHC and ELISA. It is suitable to detect JAK1 in samples from Human.

Quick Overview for JAK1 antibody (ABIN7137924)

Target: JAK1 (Janus Kinase 1 (JAK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-JAK1 Antibody

Purpose: JAK1 (Ab-1022) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa. 1020~1024 (K-E-Y-Y-T) derived from Human JAK1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for JAK1

Target: JAK1 (Janus Kinase 1 (JAK1))

Alternative Name: JAK1

Background:

Background: Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730.
Wang R, et al. (2003) Arch Biochem Biophys. 410(1): 7-15.

Aliases: JAK 1 antibody, JAK 1A antibody, JAK 1B antibody, JAK-1 antibody, JAK1 antibody, JAK1_HUMAN antibody, JAK1A antibody, JAK1B antibody, Janus kinase 1 (a protein tyrosine kinase) antibody, Janus kinase 1 antibody, JTK3 antibody, Tyrosine protein kinase JAK 1 antibody, Tyrosine protein kinase JAK1 antibody, Tyrosine-protein kinase JAK1 antibody

UniProt: P23458

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response