VASP antibody
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- Target See all VASP Antibodies
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VASP antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogen
- Peptide sequence around aa.155~159 (R-V-S-N-A) derived from Human VASP.
- Isotype
- IgG
- Top Product
- Discover our top product VASP Primary Antibody
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- Application Notes
- WB:1:500-1:1000, IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
- Alternative Name
- VASP (VASP Products)
- Synonyms
- vasp antibody, MGC80889 antibody, wu:fb23b04 antibody, wu:fk84g05 antibody, zgc:110347 antibody, si:dkey-113g17.1 antibody, si:ch211-202c21.1 antibody, DDBDRAFT_0188463 antibody, DDBDRAFT_0229340 antibody, DDB_0188463 antibody, DDB_0229340 antibody, VASP antibody, vasodilator stimulated phosphoprotein S homeolog antibody, vasodilator stimulated phosphoprotein b antibody, protein enabled antibody, vasodilator-stimulated phosphoprotein antibody, vasodilator stimulated phosphoprotein a antibody, vasodilator stimulated phosphoprotein antibody, vasp.S antibody, vaspb antibody, LOC5573842 antibody, CpipJ_CPIJ004706 antibody, CpipJ_CPIJ004707 antibody, vasP antibody, vasp antibody, VASP antibody, vaspa antibody, Vasp antibody
- Background
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Background:
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Zhao WM, et al. (2001) EMBO J 20(9): 2315-2325.
Millard TH, et al. (2005) EMBO J 24(2): 240-250.
KAliases: Vasodilator stimulated phosphoprotein antibody, Vasodilator-stimulated phosphoprotein antibody, VASP antibody, VASP_HUMAN antibody
- UniProt
- P50552
- Pathways
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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