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Estrogen Receptor alpha antibody (pSer118)

ESR1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7138414
  • Target See all Estrogen Receptor alpha (ESR1) Antibodies
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Binding Specificity
    • 30
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    pSer118
    Reactivity
    • 465
    • 167
    • 160
    • 17
    • 16
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 374
    • 98
    • 1
    • 1
    Rabbit
    Clonality
    • 357
    • 118
    • 1
    Polyclonal
    Conjugate
    • 214
    • 32
    • 21
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    • 15
    • 9
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    • 4
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    • 1
    • 1
    This Estrogen Receptor alpha antibody is un-conjugated
    Application
    • 342
    • 158
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    • 94
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    • 54
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    • 2
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    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human, Monkey, Mouse
    Purification
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    Immunogen
    Peptide sequence around phosphorylation site of serine 118 (Q-L-S(p)-P-F) derived from Human Estrogen Receptor-a.
    Isotype
    IgG
    Top Product
    Discover our top product ESR1 Primary Antibody
  • Application Notes
    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Alternative Name
    ESR1 (ESR1 Products)
    Background

    Background:

    Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

    Ramsauer VP, et al. (2003)J Biol Chem, 278(32): 30142-7.
    Jepson S, et al. (2002)Oncogene, 21(49): 7524-32.
    Ren Z, et al. (2002)J Biol Chem, 277(41): 38486-93.
    Eppenberger-Castori S, et al. (2001)J Clin Oncol, 19(3): 645-56.

    Aliases: 7*/654 isoform antibody, 7*/819 2 isoform antibody, 7*/822 isoform antibody, 8*/901 isoform antibody, 8*/941 isoform antibody, DKFZp686N23123 antibody, ER alpha antibody, ER antibody, ER-alpha antibody, Era antibody, ESR antibody, ESR1 antibody, ESR1_HUMAN antibody, ESRA antibody, Estradiol receptor antibody, Estrogen nuclear receptor alpha antibody, Estrogen receptor 1 antibody, Estrogen receptor alpha 3*,4,5,6,7*/822 isoform antibody, Estrogen receptor alpha antibody, Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform antibody, Estrogen receptor alpha delta 3*,4,5,6,7*/819 2 isoform antibody, Estrogen receptor alpha delta 4 +49 isoform antibody, Estrogen receptor alpha delta 4*,5,6,7*/654 isoform antibody, Estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform antibody, Estrogen receptor alpha E1 E2 1 2 antibody, Estrogen receptor alpha E1 N2 E2 1 2 antibody, Estrogen receptor antibody, ESTRR antibody, NR3A1 antibody, Nuclear receptor subfamily 3 group A member 1 antibody

    UniProt
    P03372
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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