SYT1/SYT2 (pThr199), (pThr202) antibody
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- Target
- SYT1/SYT2
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Binding Specificity
- pThr199, pThr202
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of threonine 202/199 (R-K-T(p)-L-N) derived from Human Synaptotagmin 1/2.
- Isotype
- IgG
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anti-SYT1/SYT2 (pSer306), (pSer309) antibody
Reactivity: Human ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
anti-SYT1/SYT2 (pThr199), (pThr202) antibodyReactivity: Human ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SYT1/SYT2
- Background
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Background:
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse
Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11, 105(10):3992-7.
Cnops L, et al. Cereb Cortex. 2008 May, 18(5):1221-31.
Lynch KL, et al. Mol Biol Cell. 2007 Dec, 18(12):4957-68.Aliases: DKFZp781D2042 antibody, FLJ42519 antibody, p65 antibody, SVP65 antibody, Synaptotagmin 2 antibody, Synaptotagmin I antibody, Synaptotagmin II antibody, Synaptotagmin-1 antibody, SYT antibody, Syt1 antibody, SYT1_HUMAN antibody, Syt2 antibody, SytI antibody
- UniProt
- P21579
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