BMX antibody (pTyr566)
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- Target See all BMX Antibodies
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
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Binding Specificity
- pTyr566
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BMX antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human, Mouse
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of Tyrosine566 (D-Q-Y(p)-V-S) derived from Human ETK.
- Isotype
- IgG
- Top Product
- Discover our top product BMX Primary Antibody
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- Application Notes
- WB:1:500-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
- Alternative Name
- BMX (BMX Products)
- Synonyms
- BMX antibody, ETK antibody, PSCTK2 antibody, PSCTK3 antibody, Etk antibody, Etk/Bmx antibody, Tyro8 antibody, RGD1565643 antibody, BMX non-receptor tyrosine kinase antibody, BMX antibody, bmx antibody, Bmx antibody
- Background
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Background:
Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility.
Zhang R, et al. (2003) J Biol Chem 278, 51267-76
Tsai YT, et al. (2000) Mol Cell Biol 20, 2043-54Aliases: Bmx antibody, BMX non receptor tyrosine kinase antibody, BMX_HUMAN antibody, BONE MARROW KINASE, X-LINKED antibody, Bone marrow tyrosine kinase gene in chromosome X protein antibody, Cytoplasmic tyrosine protein kinase BMX antibody, Cytoplasmic tyrosine-protein kinase BMX antibody, Epithelial and endothelial tyrosine kinase antibody, ETK antibody, NKT38 antibody, NTK 38 antibody, NTK38 antibody, Protein tyrosine kinase BMX antibody, PSCTK 2 antibody, PSCTK 3 antibody, PSCTK2 antibody, PSCTK3 antibody
- UniProt
- P51813
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