PUMA antibody (AA 5-23) (HRP)

Catalog No. ABIN7139742

The Rabbit Polyclonal anti-PUMA antibody has been validated for ELISA. It is suitable to detect PUMA in samples from Human.

Quick Overview for PUMA antibody (AA 5-23) (HRP) (ABIN7139742)

Target: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUMA antibody is conjugated to HRP

Application: ELISA

Product Details anti-PUMA Antibody (HRP)

Binding Specificity: AA 5-23

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Peptide sequence from Human Bcl-2-binding component 3 protein (5-23AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PUMA

Target: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Alternative Name: BBC3

Background:

Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.

Aliases: BBC 3 antibody, Bbc3 antibody, BBC3_HUMAN antibody, BCL 2 binding component 3 antibody, Bcl-2-binding component 3 antibody, BCL2 binding component 3 antibody, JFY 1 antibody, JFY-1 antibody, JFY1 antibody, p53 up regulated modulator of apoptosis antibody, p53 up-regulated modulator of apoptosis antibody, p53 Upregulated Modulator of Apoptosis antibody, PUMA alpha antibody, PUMA/JFY1 antibody

UniProt: Q9BXH1

Pathways: p53 Signaling, Positive Regulation of Endopeptidase Activity