GRF2 antibody (AA 22-40) (HRP)

Catalog No. ABIN7140101

Product Details anti-GRF2 Antibody (HRP)

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Binding Specificity: AA 22-40

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRF2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Peptide sequence from Human Rap guanine nucleotide exchange factor 1 protein (22-40AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GRF2

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Alternative Name: RAPGEF1 (RAPGEF1 Products)

Synonyms: C3G antibody, GRF2 antibody, Link-GEFII antibody, 4932418O06Rik antibody, Grf2 antibody, RAPGEF1 antibody, C3G-1 antibody, C3G-2 antibody, C3g antibody, rapgef1 antibody, zgc:56372 antibody, Rap guanine nucleotide exchange factor 1 antibody, Rap guanine nucleotide exchange factor like 1 antibody, Rap guanine nucleotide exchange factor (GEF) 1 antibody, Rap guanine nucleotide exchange factor 1 S homeolog antibody, Rap guanine nucleotide exchange factor (GEF) 1b antibody, RAPGEF1 antibody, RAPGEFL1 antibody, Rapgef1 antibody, rapgef1.S antibody, rapgef1 antibody, rapgef1b antibody, Rapgefl1 antibody

Background:

Background: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

Aliases: C3G antibody, C3G protein antibody, CRK SH3 binding GNRP antibody, CRK SH3-binding GNRP antibody, DKFZp781P1719 antibody, GRF 2 antibody, GRF2 antibody, Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) antibody, Guanine nucleotide releasing factor 2 antibody, Guanine nucleotide-releasing factor 2 antibody, OTTHUMP00000064558 antibody, Protein C3G antibody, Rap guanine nucleotide exchange factor (GEF) 1 antibody, Rap guanine nucleotide exchange factor 1 antibody, RAPGEF 1 antibody, RAPGEF1 antibody, RPGF1_HUMAN antibody

UniProt: Q13905

Pathways: Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor