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RABAC1 antibody (AA 16-299)

RABAC1 Reactivity: Candida albicans ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7380344
  • Target See all RABAC1 Antibodies
    RABAC1 (Rab Acceptor 1 (Prenylated) (RABAC1))
    Binding Specificity
    • 4
    • 1
    • 1
    • 1
    AA 16-299
    Reactivity
    • 5
    • 4
    • 1
    • 1
    Candida albicans
    Host
    • 8
    • 1
    Rabbit
    Clonality
    • 8
    • 1
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    This RABAC1 antibody is un-conjugated
    Application
    • 7
    • 6
    • 2
    ELISA, Western Blotting (WB)
    Cross-Reactivity
    Candida albicans
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Candida albicans pH-regulated antigen PRA1 protein (16-299AA)
    Isotype
    IgG
    Top Product
    Discover our top product RABAC1 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RABAC1 (Rab Acceptor 1 (Prenylated) (RABAC1))
    Alternative Name
    PRA1 (RABAC1 Products)
    Synonyms
    PRA1 antibody, PRAF1 antibody, YIP3 antibody, 2310040I06Rik antibody, Gbpap1 antibody, prenylin antibody, Pra1 antibody, wu:fe26d12 antibody, zgc:86749 antibody, MGC81207 antibody, pra1 antibody, yip3 antibody, praf1 antibody, MGC146421 antibody, F22K20.5 antibody, F22K20_5 antibody, Rab acceptor 1 antibody, Rab acceptor 1 (prenylated) antibody, Rab acceptor 1 (prenylated) S homeolog antibody, Rab acceptor 1 (prenylated) L homeolog antibody, Regulator of chromosome condensation (RCC1) family with FYVE zinc finger domain-containing protein antibody, RABAC1 antibody, Rabac1 antibody, rabac1 antibody, rabac1.S antibody, rabac1.L antibody, PRAF1 antibody
    Background

    Background: Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion and migration. As a surface protein, binds the two human complement regulators CFH and CFHR1, as well as plasminogen PLG, mediates complement evasion and extra-cellular matrix interaction and/or degradation. As a released protein, enhances complement control in direct vicinity of the yeast and thus generates an additional protective layer which controls host complement attack, assisting the fungus in escaping host surveillance. Binds to host fluid-phase C3 and blocks cleavage of C3 to C3a and C3b, leading to inhibition of complement activation. Mediates also human complement control and complement evasion through binding to C4BPA, another human complement inhibitor, as well as through binding to host integrin alpha-M/beta-2. Decreases complement-mediated adhesion, as well as uptake of C.albicans by human macrophages.

    Aliases: PRA1 antibody, FBP1 antibody, CAALFM_C406980WA antibody, CaO19.10623 antibody, CaO19.3111 antibody, pH -regulated antigen PRA1 antibody, 58 kDa fibrinogen-binding mannoprotein antibody

    UniProt
    P87020
    Pathways
    Chromatin Binding
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