GadA (AA 1-466) antibody (Biotin)

Catalog No. ABIN7141512

Product Details

Target: GadA

Binding Specificity: AA 1-466

Reactivity: E. coli

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: ELISA

Cross-Reactivity: E. coli

Purification: >95%, Protein G purified

Immunogen: Recombinant Escherichia coli Glutamate decarboxylase alpha protein (1-466AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: GadA

Background:

Background: Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.

Aliases: gadA antibody, gadS antibody, b3517 antibody, JW3485Glutamate decarboxylase alpha antibody, GAD-alpha antibody, EC 4.1.1.15 antibody

UniProt: P69908