SERPINA1 antibody (AA 25-418) (Biotin)

Catalog No. ABIN7143756

Product Details anti-SERPINA1 Antibody (Biotin)

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Binding Specificity: AA 25-418

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Alpha-1-antitrypsin protein (25-418AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SERPINA1

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Alternative Name: SERPINA1 (SERPINA1 Products)

Synonyms: AACT antibody, ACT antibody, GIG25 antibody, A1AT antibody, PI antibody, alpha-1-PI antibody, A1A antibody, AAT antibody, PI1 antibody, PRO2275 antibody, alpha1AT antibody, Pi antibody, Spi1 antibody, MGC64429 antibody, serpina1d antibody, Aps antibody, SERPINA3-5 antibody, serpin family A member 3 antibody, alpha-1-antiproteinase F precursor antibody, serpin family A member 1 antibody, alpha-1-antitrypsin antibody, calumenin antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antibody, SH2B adaptor protein 2 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog antibody, SERPINA3 antibody, LOC100008973 antibody, SERPINA1 antibody, LOC100328621 antibody, CALU antibody, Serpina1 antibody, serpina1.S antibody, serpina1 antibody, SPIA5 antibody, Sh2b2 antibody, Calu antibody, serpina1.L antibody

Background:

Background: Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).

Aliases: A1A antibody, A1AT antibody, A1AT_HUMAN antibody, AAT antibody, Alpha 1 antiproteinase antibody, Alpha 1 antitrypsin antibody, Alpha 1 antitrypsin null antibody, Alpha 1 protease inhibitor antibody, Alpha-1 protease inhibitor antibody, Alpha-1-antiproteinase antibody, alpha1 proteinase inhibitor antibody, Alpha1AT antibody, Dom1 antibody, PI antibody, PI1 antibody, PRO0684 antibody, PRO2275 antibody, Serine (or cysteine) proteinase inhibitor clade A member 1 antibody, Serine protease inhibitor 1-1 antibody, Serine protease inhibitor A1a antibody, Serpin A1 antibody, Serpin A1a antibody, Serpin peptidase inhibitor clade A member 1 antibody, Serpina1 antibody, Short peptide from AAT antibody, SPAAT antibody, Spi1-1 antibody

UniProt: P01009