ASZ1 antibody (AA 1-200) (Biotin)

Catalog No. ABIN7144248

Product Details anti-ASZ1 Antibody (Biotin)

Target: ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain Containing 1 (ASZ1))

Binding Specificity: AA 1-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASZ1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein (1-200AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ASZ1

Target: ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain Containing 1 (ASZ1))

Alternative Name: ASZ1 (ASZ1 Products)

Synonyms: Gasz antibody, GASZ antibody, gasz antibody, MGC56332 antibody, zgc:56332 antibody, ALP1 antibody, ANKL1 antibody, C7orf7 antibody, CT1.19 antibody, Orf3 antibody, 4933400N19Rik antibody, ORF3 antibody, ankyrin repeat, SAM and basic leucine zipper domain containing 1 antibody, Asz1 antibody, ASZ1 antibody, asz1 antibody

Background:

Background: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

Aliases: ASZ1 antibody, ALP1 antibody, ANKL1 antibody, C7orf7 antibody, GASZAnkyrin repeat antibody, SAM and basic leucine zipper domain-containing protein 1 antibody, Ankyrin-like protein 1 antibody, Germ cell-specific ankyrin antibody, SAM and basic leucine zipper domain-containing protein antibody

UniProt: Q8WWH4