ABCG2 antibody (AA 296-371)

Catalog No. ABIN7372520

Product Details anti-ABCG2 Antibody

Target: ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))

Binding Specificity: AA 296-371

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCG2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human ATP-binding cassette sub-family G member 2 protein (296-371AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ABCG2

Target: ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))

Alternative Name: ABCG2 (ABCG2 Products)

Synonyms: bcrp antibody, ABCG2 antibody, ABC15 antibody, ABCP antibody, BCRP antibody, BCRP1 antibody, BMDP antibody, CD338 antibody, CDw338 antibody, EST157481 antibody, GOUT1 antibody, MRX antibody, MXR antibody, MXR1 antibody, UAQTL1 antibody, AI428558 antibody, Bcrp1 antibody, ABCG3 antibody, ATP binding cassette subfamily G member 2 antibody, ATP binding cassette subfamily G member 2 (Junior blood group) antibody, ATP binding cassette subfamily G member 2 (Junior blood group) L homeolog antibody, ATP-binding cassette, sub-family G (WHITE), member 2 antibody, ATP-binding cassette sub-family G member 2 antibody, ABCG2 antibody, abcg2 antibody, abcg2.L antibody, Abcg2 antibody, LOC100008640 antibody

Background:

Background: High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.

Aliases: ABC transporter antibody, ABC15 antibody, ABCG 2 antibody, ABCG2 antibody, ABCG2_HUMAN antibody, ABCP antibody, ATP binding cassette sub family G (WHITE) member 2 antibody, ATP binding cassette transporter G2 antibody, ATP-binding cassette sub-family G member 2 antibody, BCRP antibody, BCRP1 antibody, BMDP antibody, Breast cancer resistance protein antibody, CD338 antibody, CDw338 antibody, CDw338 antigen antibody, EST157481 antibody, GOUT1 antibody, MGC102821 antibody, Mitoxantrone resistance associated protein antibody, Mitoxantrone resistance-associated protein antibody, MRX antibody, Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody, MXR antibody, MXR1 antibody, Placenta specific ATP binding cassette transporter antibody, Placenta specific MDR protein antibody, Placenta-specific ATP-binding cassette transporter antibody, UAQTL1 antibody

UniProt: Q9UNQ0

Pathways: Transition Metal Ion Homeostasis