GRK2 antibody (AA 2-221)
Quick Overview for GRK2 antibody (AA 2-221) (ABIN7145433)
Target
See all GRK2 (ADRBK1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 2-221
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Beta-adrenergic receptor kinase 1 protein (2-221AA)
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Isotype
- IgG
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anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 398-640) antibody
ADRBK1 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 440-689) antibodyADRBK1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibodyKO Validated ADRBK1 Reactivity: Human WB, IHC (p), ICC, IF, IP, FACS Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibodyADRBK1 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IHC, ICC Host: Mouse Monoclonal 3F8 unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (Internal Region) antibodyADRBK1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 633-660), (C-Term) antibodyADRBK1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB0982 unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibodyADRBK1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (N-Term) antibodyADRBK1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibodyADRBK1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (Internal Region) antibodyVerified ADRBK1 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
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Application Notes
- Recommended dilution: IHC:1:500-1:1000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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Alternative Name
- GRK2
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Background
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Background: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
Aliases: ADRBK1 antibody, Adrenergic beta receptor kinase 1 antibody, ARBK1_HUMAN antibody, BARK antibody, BARK1 antibody, Beta adrenergic receptor kinase 1 antibody, Beta ARK 1 antibody, Beta ARK1 antibody, Beta-adrenergic receptor kinase 1 antibody, Beta-ARK-1 antibody, FLJ16718 antibody, G protein coupled receptor kinase 2 antibody, G-protein coupled receptor kinase 2 antibody, GRK2 antibody
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UniProt
- P25098
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
Target
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