CLEC4C antibody (AA 45-213) (Biotin)

Catalog No. ABIN7358669

Product Details anti-CLEC4C Antibody (Biotin)

Target: CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))

Binding Specificity: AA 45-213

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC4C antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human C-type lectin domain family 4 member C protein (45-213AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CLEC4C

Target: CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))

Alternative Name: CLEC4C (CLEC4C Products)

Synonyms: BDCA2 antibody, CD303 antibody, CLECSF11 antibody, CLECSF7 antibody, DLEC antibody, HECL antibody, PRO34150 antibody, Clec4c antibody, C-type lectin domain family 4 member C antibody, CLEC4C antibody, LOC100733227 antibody

Background:

Background: Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.

Aliases: CLEC4C antibody, BDCA2 antibody, CLECSF11 antibody, CLECSF7 antibody, DLEC antibody, HECL antibody, UNQ9361/PRO34150C-type lectin domain family 4 member C antibody, Blood dendritic cell antigen 2 antibody, BDCA-2 antibody, C-type lectin superfamily member 7 antibody, Dendritic lectin antibody, CD antigen CD303 antibody

UniProt: Q8WTT0